Overview / Review

Clinical Care Guidelines / Pathways

The following are clinical care guidelines for the evaluation and treatment of DMD:

REQUIRED: DMD Guidelines Part 1 - Diagnosis, neuromuscular, rehabilitation, endocrine, GI, Nutrition - Review - Lancet 2018
REQUIRED: DMD Guidelines Part 2 - Respiratory, cardiac, bone health, and orthopedic - Review - Lancet 2018
REQUIRED: DMD Guidelines Part 3 - Primary care, emergency management, psychosocial care, and transitions of care across the lifespan - Review - Lancet 2018

Rehabilitation Care

REQUIRED: Rehab in DMD: Case et al Rehabilitation Management of the patient the DMD Pediatrics 2018.pdf

Developing Expertise

Steroid treatment - long term outcomes: McDonald CM, Henricson EK, Abresch RT, Duong T, Joyce NC, Hu F, Clemens PR, Hoffman EP, Cnaan A, Gordish-Dressman H; CINRG Investigators. Long-term effects of glucocorticoids on function, quality of life, and survival in patients with Duchenne muscular dystrophy: a prospective cohort study. Lancet. 2018 Feb 3;391(10119):451-461. doi: 10.1016/S0140-6736(17)32160-8. Epub 2017 Nov 22. PMID: 29174484.
Natural History (2024): McDonald CM, Signorovitch J, Mercuri E, et al. Functional trajectories before and after loss of ambulation in Duchenne muscular dystrophy and implications for clinical trials. PLoS One. 2024;19(6):e0304099. Published 2024 Jun 3. doi:10.1371/journal.pone.0304099
Natural History (2019): Coratti et al. Longitudinal natural history in young boys with DMD. Neuromuscular Disorders 2019
Orthopedic / Surgical Management: Apkon et al. Orthopedic and surgical management of the patient with DMD. Pediatrics 2018
Historic Treatment - Steroids: Moxley et al. Practice Parameter - Corticosteroid treatment of Duchenne dystrophy. Neurology 2005

Living with...

Active Research in DMD: Parent Project Muscular Dystrophy website
Cure Duchenne Organization: information about DMD education for families, DME, school modification